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Staff profile for Dr Paul Wrigley

Position

Pain Medicine Senior Staff Specialist, Clinical Senior Lecturer, Research Fellow & Supervisor of Training (Faculty of Pain Medicine)

Job description

Pain Specialist

Organisation

Pain Specialist, University of Sydney

Qualifications

MBBS, MM, PhD, FANZCA, FFPMANZCA

Education

Medicine, Anaesthesia and Pain Medicine.

Research interests

Brain mechanisms in spinal cord injury neuropathic pain.

Neuroimaging (fMRI, MRS, Voxometry, DTI, Tractography, CASL)

Spinal cord mechanisms of nociception and thermoreception.

PhD thesis topic “Thermal processing in the spinal cord”.

Project

Pain following spinal cord injury (SCI): understanding mechanism to develop treatments

Pain following spinal cord injury: relationship to integrity of spinal pathways

Cortical and fibre tract changes in subjects with neuropathic pain following SCI

Structural alterations of the human brain following complete SCI in people with and without neuropathic pain - a pilot study

Development of an Australian spinal cord injury pain research database

Thermal processing in the spinal cord (PhD)

Grants/Awards

Grants

  • Pfizer Neuroscience Research Grant 2007
  • ANZCA Trials Group Pilot Grant 2007
  • NHMRC Medical and Dental Scholarship (2002 – 2005) Research Grant
  • Australian and New Zealand College of Anaesthetists (2002 – 2005)
  • Pfizer Neuroscience Research Grant (2004)
  • Postgraduate Research Support Scheme Funding (2002 & 2003)
  • Anthony Pierre Balthazar Research Grant (2002 & 2004)
  • Nic Jools Pain Research Scholarship (2004)
Prizes
  • Gilbert Brown Research Prize, Australian and New Zealand College of Anaesthetists 2005
  • Harry Daly Research Award, Australian and New Zealand College of Anaesthetists 2002
  • Barbara Walker Prize for Excellence in Pain Medicine 2000

Publications

Peer reviewed:

Gustin S, Wrigley PJ, Nash PG, Macefield VG, Gandevia SC, Cousins MJ, Henderson LA, Siddall PJ. Movement imagery evokes pain in spinal cord injured patients. Pain 2007:doi:10.1016/j.pain.2007.1008.1032

Wrigley PJ, Siddall PJ. Pharmacological interventions for neuropathic pain in spinal cord injury. Topics in Spinal Cord Injury Rehabilitation. 2007(in press).

Smeal WL, Yezierski RP, Wrigley PJ, Siddall PJ, Jensen MP, Ehde DM. Spinal cord injury. Journal of Pain 2006;7(12):871-877.

Wrigley, P.J., Elliott, D. & Blake, D. (1998). A Phase 2 Clinical Trial Comparing Ro 48-6791, a New Short-Acting Benzodiazepine, with Propofol for Induction of Anaesthesia. Anaesthesia and Intensive Care, 26, 509-514.

Book chapters:

Siddall PJ, Wrigley PJ. Spinal cord injury. In: Rice A, Howard RF, Justins DM, Miaskowski CA, Newton-John T, editors. Textbook of Clinical Pain Management. London: Hodder Arnold; In press.

Wrigley PJ, Siddall PJ, editors. Clinical evaluation of pain. Hong Kong: Hong Kong University Press; In press.

Other:

Gustin S, Wrigley PJ, Nash PG, Macefield VG, Gandevia SC, Cousins MJ, et al., editors. Structural changes associated with pain in spinal cord injured patients. Second international congress on neuropathic pain; 2007; Berlin.

Wrigley PJ, Gustin SM, Middleton JW, Macefield VG, Gandevia SC, Nash PG, et al., editors. Human motor cortex anatomical changes following spinal cord injury. 13th Annual Meeting Human Brain Mapping; 2007; Chicago, Illinois.

Wrigley PJ, Vaughan CW, editors. Spinal mechanisms of thermal nociceptive processing. 11th World Congress on Pain; 2005; Sydney. International Association for the Study of Pain.

Wrigley, P.J. & Vaughan, C.W. (2003). Cold afferent inputs activate a subpopulation of rat dorsal horn neurons in vitro. In Proceedings of the Australian Neuroscience Society. Adelaide Convention Centre.

Wrigley, P.J. & McCulloch, T. (2002). Complementary Medicine and Pain Medicine. The Australian Pain Society Newsletter, November, 4-7

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Pain Management Research Institute